Staphylococcus epidermidis — the 'accidental' pathogen

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Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interaction.

Staphylococcus aureus exhibits a strong capacity to attach to abiotic or biotic surfaces and form biofilms, which lead to chronic infections. We have recently shown that Esp, a serine protease secreted by commensal Staphylococcus epidermidis, disassembles preformed biofilms of S. aureus and inhibits its colonization. Esp was expected to degrade protein determinants of the adhesive and cohesive ...

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ژورنال

عنوان ژورنال: Nature Reviews Microbiology

سال: 2009

ISSN: 1740-1526,1740-1534

DOI: 10.1038/nrmicro2182